Glyconutrients
Glyconutrients sugar health
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  Science has proven that your body uses glyconutrients to prevent infections and disease, and slow the aging process. The medical literature documents improvement in every major category of disease, including conditions like diabetes, heart disease, chronic fatigue syndrome, fibromyalgia, hepatitis C, cancer, autism, ADD, ADHD, dyslexia, candida infections, asthma, menopause, Tat-Sachs disease, urinary infections, upper respiratory infections, stroke, cerebral palsy, organ transplant, depression, muscular dystrophy, failure to thrive in infants, alcoholism, improvement in antioxidant defense, and many more.

 
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The very areas of health that are the biggest challenges to modern medicine are the areas that body seems very capable of improving when given the right tools.

The effectiveness of glyconutrients as the key to proper cellular communication and proper cell function has been established by the world's leading scientists and researchers. This research and the growing realisation amongst doctors and the general public will be the driving determinant for glyconutritionals playing a leading role in the 21st century's emerging wellness industry

Optimal health is a lifetime commitment. Unlike pharmaceutical drugs that mostly treat symptoms, nutritional supplementation acts as prevention as well as increasing the body's ability to heal, repair, regenerate, regulate and protect itself. It therefore requires a lifetime commitment

As we've seen in controlled studies in humans and animals, the saccharides [glyconutrients] in combination with adequate amounts of other key essential nutrients, accelerate healing, improve immune function, slow down ageing, improve memory, lower anxiety without toxic side effects. When health is improved or restored, mind and body shift over to what the Chinese call 'the right side', embracing harmony, healing and 'gong'.

Dr Emil Mondoa,
MD Pediatrician and Scientific Researcher

MANNOSE GALACTOSE
FUCOSE GLUCOSE
N-ACETYLGALACTOSAMINE N-ACETYLNEUROMINIC ACID
N-ACETYLGLUOSAMINE XYLOSE

 

 

 

 


 

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MANNOSE

  • A remedy for urinary tract infections (UTIs). The bladder lining is comprised of polysaccharide molecules. Finger-like projections on the cell surface of E.coli bacteria adhere to these molecules, initiating an infection. When Mannose molecules are present, E.coli prefers to attach to them to form a complex which is then expelled with the next voiding. Studies have also shown that about 80% of painful bladder syndromes become symptom-free when a Mannose supplement is added to the diet.
  • Prompts anti-inflammatory activity and tissue regeneration. It appears to have an active role in the activation of macrophages, whose function it is to clean up debris which can cause inflammation. Mannose stimulates fibroblasts to make more collagen and proteoglycans, which means that healing is speeded up, pain is lessened, and skin integrity returns to normal faster. Mannose also works to correct over-active neutrophils (T cells) that cause misguided inflammation. Mannose displaces certain enzymes required for T cells to flow into various areas such as the joints, liver tissue, kidneys, and even central nervous system areas, thereby acting as a natural anti-inflammatory agent.
  • Mannose, Galactose, Fucose, and N-acetylneuraminic acid are all involved in reversing Failure to thrive (FFT) syndromes. Failure to thrive and cachexia (general ill health and malnutrition) are also seen in adults with AIDS and cancer. Studies show that a direct cause of FTT symptoms in children is the failure of glycoproteins to transport sugar, something that can actually start in the placenta. This malfunction of glucose transporters (glycoproteins) can also occur in the blood-brain barrier and muscle cells of the developing infant, inevitably producing a host of undesirable symptoms. Research has shown that supplementation with glyconutrients resulted in significantly improved conditions.
  • Capable of activating insulin-like growth factor receptors, implying it can be beneficial for diabetics.
  • Crucial for joint protection, especially in cases of rheumatoid arthritis. Genetic mutations in, or the lack of, mannose-binding proteins can predispose a person to the disease; but, by adding glyconutrients to the diet, such miscommunication between immune cells is corrected.
  • Proven to reduce tumor growth and increase survival rates of cancerous animals. It appears that the sugar stimulates macrophages which secret interferons. These, in turn, activate natural killer cells involved in the elimination of cancer cells.
  • Acts as an antibacterial agent. Bacteria have lectins on their surfaces that bind to host cells, resulting in infection. However, Mannose competes with the bacterial lectins, occupying sites that would normally bind to host cell Mannose receptors, thus preventing attachment and thwarting possible infection.

 

 


 

GALACTOSE

  • Inhibits tumor growth and its spread (metastasis), especially to the liver.
  • Help correct many disorders, including enhancing wound healing, decreasing inflammation, and stimulating calcium absorption. It also appears to help lower the risk of developing cataracts.
  • Studies also indicate galactose triggers long-term memory formation.
  • Found in both the proximal and distal tubules of the kidney, important for proper kidney function.
  • Present in intestinal mucins which inhibit cholesterol absorption.
  • Play a primary role in the immune system, especially that of rheumatoid arthritis. In such patients, blood levels of the sugar were markedly reduced and proved that the less Galactose there was available, the more severe was the disease. During remission, the reduction in the amount of Galactose was reversed.
  • Important in maintaining normal bacterial flora in the intestines. Prolonged use of Galactose has proven to increase the number of Bifidobacteria while providing the proper environment for other beneficial bacteria in the human gut. Providing this type of environment not only strengthens digestive abilities, but also the immune system.
  • A link seen between Galactose deficiency and MS (multiple sclerosis). This disorder has already been linked to an inablility to absorb another essential sugar, Xylose, but there also appears to be abnormal Galactose molecules present as well. In addition, the myelin sheath that covers nerves is attacked by overactive immune cells. The myelin sheath contains Galactose, as well as other essential sugars. Therefore, supplementation of all eight essential sugars could help rebuild the system to where absorption is once again possible and could reverse the condition. 

FUCOSE

  • Essential part of eliminating or reversing such disease processes as cancer, inflammation, and immunity.
  • Important for efficient neuron transmission in the brain. According to studies, Fucose is known to influence brain development and may also help improve the brain’s ability to create long-term memories.
  • A powerful immune modulator. It is distributed in macrophages, which are critically important to immune function. There have been numerous well-documented benefits for its necessity in immune function ,especially that of an overactive immune system, the cause of autoimmune disorders.
  • The ability to suppress such allergic skin reactions as contact dermatitis.
  • Ability to kill bacteria and to help fortify resistance to infection,  particularly true of respiratory cells.
  • Plays a significant role in many diseases, including cancer and its spread. Research is still ongoing but showing promise in the areas of inhibiting and reversing leukemia and breast cancer, including the suppression of tumor growth. Some studies have concluded that Fucose and Mannose appeared to be the most effective of the essential sugars when it came to slowing the growth of cancer cells. 

 
GLUCOSE

  • potent fast-energy source, Glucose is easily absorbed into the bloodstream.
  • Enhances memory, stimulates calcium absorption, and increases cellular communication. However, too much can raise insulin levels, leading to obesity and diabetes; but too little can cause hypoglycemia or  insulin shock (diabetic coma).
  • Vital to brain function, Glucose metabolism is disturbed in depression, manic-depression, anorexia, and bulimia.
  • Alzheimer’s patients, for instance, register much lower glucose levels than those with other forms of brain malfunction that resulted from stroke or other vascular disease.
  • Absorbed into liver cells, Glucose reduces the secretion of Glucagon, resulting in an increased uptake of Glucose by muscle and fat tissue cells.
  • Normal amounts of Glucose at a level that did not cause digestive symptoms has a beneficial effect on intestinal flora, especially that of bifidobacteria, vital for proper digestion and nutrient uptake.
  • Significant reduction in ratings of urges to smoke when smokers were given Glucose tablets to chew compared to groups who were given Sorbitol tablets. This finding suggests a glucoregulation link and cigarette cravings and true for alcoholics.
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N-ACETYLGALACTOSAMINE

  • Enhance cellular communication. levels of N-acetylgalactosamine are altered in certain diseases, suggesting that it plays an important role in the prevention of those diseases.
  • May inhibit the growth of some tumors. For example, colon cancer patients have only half the normal amounts of N-acetylgalactosamine. Studies have shown that colon cancer cells that metastasize make more mucin, making them more likely to form metastases. Therefore, it appears that N-acetylgalactosamine plays an important role in preventing this formation from occurring.
  • Lower than normal levels have been found in patients with heart disease implying that these conditions may be reversed if a supplementation of N-acetylgalactosamine were to be added
  • Plays a role in joint function
  • An important role in the immune system. Contained in macrophages and neutrophils, it may play a significant role in the etiolology of joint inflammation and could be important in such conditions as rheumatoid arthritis.
  • Localized in the golgi apparatus and endoplasmic reticulum – found in cell organelles and associated with synthesis of various proteins and enzymes.
  • Important in nerve function.
  • Concentrated in other sensory nerve structures especially in the retina, photoreceptors, optic nerve, and the epithelial pigment of the eyes of both humans and animals- may be extremely important for optimal vision.
  • Important in the functional role of certain tissues. Some of these tissues include the ducts of the kidney, the testes, the skin, and a variety of other structures including sweat glands, some blood vessel cells, and hair follicles.
  • Decrease with age, implying that age-deterioration of various body functions could be held off with the addition of this saccharide to the diet.

 


 

N-ACETYLNEUROMINIC ACID
(sialic acid)
 

  • An immune moderator that affects the flow resistance of mucus- repels bacteria, viruses, and other harmful microbes. Also, shown to inhibit strains of influenza A and B viruses more effectively than any prescription antivirals. In the April 2001 issue of Protein Science, scientists from Australia reported findings that showed sialic acid was an effective antiflu agent. Another study reported in a 1995 issue of Antimicrobial Agents and Chemotherapy, stated that a sialic acid mixture was up to 1000 times more effective in fighting influenza than potent antiviral drugs.
  • High levels are found in the human brain and kidney, it is speculated that sialic acid may play a key role in brain development and learning and in lessening the risk of kidney stone formation.
  • Found in such other tissues as the skin and testes leading to speculation that disruptions like skin diseases and reproductive problems could be reversed.
  • Influences blood coagulation and cholesterol levels, lowering LDL (bad cholesterol).
  • In alcoholics as well as those with Sjögren’s syndrome, levels are altered, suggesting that supplementation could reverse these disorders.
  • Abnormalities in sialic acid metabolism are seen in infants who fail to grow, who regress in development, who have enlarged livers and/or spleens, who show a coarsening of facial features, and who display a failure to produce pigmentation of the skin and hair.
  • Important during pregnancy and lactation. Levels are increased during these stages indicates the need for these sugars by the developing infant both for establishing immunity and for its physical and mental development.
  • Levels are decreased in the upper airway cells- important barrier for preventing opportunistic respiratory infections seen in severely ill patients.
  • Reduced in those with rheumatoid arthritis, confirming that this saccharide plays an important part in the immune system.
  • Researchers at Kumamoto University in Japan discovered that sialic acid blocked the release of histamine, thus decreasing the severity of allergic reactions as well as asthmatic bronchial spasms.

 


               
N-ACETYLGLUCOSAMINE
                  

  • Helps repair cartilage while decreasing pain and inflammation. It also seems to increase the range of motion in osteoarthritis. Injuries to the joints also heal more rapidly when this is added. Is attracted to and directly involved in the repair of damaged cartilage. Based on these findings, scientists are now speculating that Glucosamine may also help generalized wound repair. 
  • Deficiencies or malfunctions in the ability to metabolize have been linked to diseases of the bowel and bladder. Glucosamine has been shown to help repair the mucosal-lining defensive barrier called the glycosaminoglycan layer (GAG). Defects in the GAG layer have been implimented in Crohn’s disease, Ulcerative Colitis, and Interstitial Cystitis. 
  • An immune modulator with antitumor and antiviral properties, as well as activity against HIV-prevented the human influenza virus and the herpes virus. 
  • Ability to reduce the progression of experimental cancers. For instance, the growth of Ehrlich ascites tumors in mice were inhibited simply by adding the essential sugars Mannose and Glucosamine into their drinking water.
  • vital to learning.
  • Found in mammalian brains, suggesting a role in nerve function. This would also tie in with its role in the learning process. 
  • Thyroid gland is known to have N-acetylglucosamine receptors on its surface which are believed to play a role in the transport of thyroglobulin (an iodine-containing glycoprotein)
  • Found in several tissues and organs, especially the , it is readily assumed that Glucosaminliver, small intestine, testes, epithelial cells of the endocrine and sebaceous glands, and endothelial cells of blood vesselse plays an important role in these areas.
  • Retinal tissue from human eye donors showed that Glucosamine readily preferred the photoreceptor layer of the retina, suggesting that, not only this sugar is needed for vision, but the others as well since several essential sugar concentrations have been found in the eye structure. 
  • Found in the intestinal mucin, which binds chloresterol, thereby limiting its absorption. 
  • Proven to decrease insulin secretion without suppressing liver glucose production.

    XYLOSE
  • An antibacterial and antifungal, particularly with gram negative organisms and Candida.
  • Proving to help prevent cancer of the digestive tract.
  • Absorption rate of Xylose is decreased in some patients with intestinal disorders, including those with colitis and diabetes, suggesting that when absorption problems are corrected, these conditions might also reverse themselves.
  • Promotes the growth of “friendly flora” in the intestines, thus increasing the manufacture and absorption of all nutrients. This aspect is necessary in strengthening the immune system to help fight off any type of illness. 

 

 

Facts and information for glyconutrients and each saccharide was obtained from:http://www.innvista.com/

 


     
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